D-二聚体在肺栓塞疾病诊断中的应用研究

目的：探讨肺栓塞患者中血浆D-二聚体（DD）含量的变化,为肺栓塞疾病（PE）的早期诊断提供依据。方法：采用免疫比浊法检测肺栓塞住院患者和非肺栓塞患者D-二聚体的含量。结果：肺栓塞患者血浆D-二聚体（DD）含量均值为（3.01±2.81）μg/ml,非肺栓塞患者为（1.11±0.90）μg/ml,前者显著高于后者（P〈0.01）。结论：血浆D-二聚体测定可作为诊断肺栓塞疾病的重要指标之一,特别对于临床低概率肺栓塞疾病的排查具有非常重要的临床价值。

Application of D--dimer on pulmonary embolism disease diagnosis

Objective：To explore the changes of D--dimer （DD） level in blood of pulmonary embolism patients to provide clinical value for the early diagnosis. Methods： D--dimer level of pulmonary embolism in inpatients and outpatients was detected by immunoturbidimetry. Results： The average level of D--dimer was （3.01±2.81） vg/ml and （1.11±0.90） vg/ml in the pulmonary embolism group and control group, respectively, which was significantly increased in pulmonary embolism group （P〈0.01）. Conclusion： The level of D--dimer can be used as one of the important targets for the pulmonary embolism diagnosis, espe- cially to investigate the low risk pulmonary embolism disease in clinic.