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门诊口服卡莫氟治疗晚期消化道肿瘤
引用本文:胡卫东,袁宏银,高幼军. 门诊口服卡莫氟治疗晚期消化道肿瘤[J]. 肿瘤学杂志, 2002, 8(5): 272-273
作者姓名:胡卫东  袁宏银  高幼军
作者单位:武汉大学中南医院,湖北武汉430071
摘    要:目的 研究卡莫氟对晚期消化道肿瘤的疗效及改善生存质量的效果。方法 对35例不能手术的晚期消化道肿瘤患者在门诊使用卡莫氟,450mg/d-600mg/d,每例至少服药20g以上,结果 CR1例,PR10例,总有效率31.4%,Karnofsky评分提高,主要毒副作用为轻度骨髓抑制和消化道症状。结论 门诊口服卡莫氟治疗晚期消化道肿瘤安全、有效。

关 键 词:门诊 口服 卡莫氟 治疗 晚期消化道肿瘤 疗效
文章编号:1671-170X(2002)05-0272-02
修稿时间:2002-07-19

A Study of Carmofur in Treatment of Advanced Digestive Tract Cancer for Out-patients
HU Wei-dong,YUAN Hong-yin,GAO You-jun. A Study of Carmofur in Treatment of Advanced Digestive Tract Cancer for Out-patients[J]. Journal of Chinese Oncology, 2002, 8(5): 272-273
Authors:HU Wei-dong  YUAN Hong-yin  GAO You-jun
Abstract:[Purpose] To evaluate the effect of carmofur (HCFU) in treatment of digestive tract cancer and the effect of improving quality of life for out-patients.[ Method ] Thirty-five patients with digestive tract cancer who were not suitable for operation were treated with carmofur for out-patients, 450mg - 600mg per day with total dose at least 20g. [Results] The response rate was 31.4% (CR 1 cases and PR 10 cases) .The Kamofsky score was raised in nearly half of patients.The major side effects including marrow suppression and digestive toxicity were slight . [ Conclusion ] It is effective and safe to treat advanced digestive tract cancer patients with carmofur for out-patients.
Keywords:digestive tract cancer  drug therapy  carmofur  side effect  efficacy
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