不同剂量米非司酮用于紧急避孕的结果分析

目的观察米非司酮两种剂量用于紧急避孕的临床效果。方法 120例受试者按米非司酮剂量不同,分为米非司酮25mg(A组)60例和米非司酮10mg(B组)60例,观察服药后的不良反应及月经情况、阴道流血情况等。结果 A、B组避孕成功率分别为86.6%和88.3%,组间比较无显着性差异(χ2=2.75,P>0.05);A、B组月经趋于正常者分别为63.3%和61.6%(χ2=2.99,P>0.05);A、B组不良反应11例(18.3%)和B组9例(15.0%)(χ2=2.35,P>0.05)。结论两组在避孕效果、不良反应及月经变化等方面均无明显差异,低剂量米非司酮用于紧急避孕同样有效。

Analysis of Emergency Contraception use Mifepristone by Different Doses

Objective To observe the two doses of mifepristone for emergency contraception clinical effects. Methods 120 cases of subjects According to the different doses of mifepristone were divided into mifepristone 25mg （A group） 60 cases and mifepristone 10mg （B group） 60 cases, The side effects and menstrual cases, vaginal bleeding after medication were observed. Results The success rate of contraceptive in A, B group were 88.36% and 89.56% （χ^2=2.75, P〉0.05）; The normal menstruation in A, B group were 63.3% and 61.6% （χ^2=2.99,P〉0.05）. Conclusion The contraceptive effectiveness, side effects and menstrual in two groups were no significant differences The Low-dose mifepristone for emergency contraception to be effective.