利用磁共振成像实现肿瘤热疗中实时无创测温的方法

肿瘤热疗特别是高强度聚焦超声（HIFU）技术，已成为一种重要且非常具有前景的肿瘤治疗方法，温度是直接决定热疗效果的重要参数，实时准确的进行深部无创测温是目前制约肿瘤热疗进一步发展的一项关键技术。近来利用磁共振成像（MRI）进行无创测温，正受到越来越多的研究者的重视。本文简述了MRI无创测温的三种方法，比较了不同测温原理的特点和适用条件，报道了已有研究发展状况，并介绍了尚待解决的问题。

Real-time and Non-invasive Temperature Monitoring of Thermotherapy Using MRI

High-intensity focused ultrasound(HIFU) thermotherapy is a promising technique for local tumor destruction of solid organs.Temperature is the important parameter which impacts the curative effects of thermotherapy.For safety and efficiency reasons,it is necessary to monitor the temperature changes inside body in real-time,non-invasively and precisely.Recently MRI methods employed for temperature monitoring during HIFU therapy have been paid more and more attentions to.This paper introduces the general principles of non-invasive temperature monitoring using MRI.The authors also review the development of this technique and point out some problems that need to be solved.