| 3，4－二羟基苯乙酮对家兔缺血－再灌心肌的影响 |
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| 引用本文： | 崔晓明,郭绢霞,宋惠萍,曾庆善. 3，4－二羟基苯乙酮对家兔缺血－再灌心肌的影响[J]. 中南大学学报(医学版), 1994, 0(1) |
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| 作者姓名： | 崔晓明 郭绢霞 宋惠萍 曾庆善 |
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| 作者单位： | 杭州浙江医院 |
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| 摘 要： | 以超微结构、线粒体形态计量及ＬＤＨ，ＳＯＤ活性为依据，探讨３，４－二羟基苯乙酮（ＤＨＡＰ）对家兔缺血－再灌心肌细胞的影响。结果表明：ＤＨＡＰ组缺血－再灌心肌细胞的损伤、ＬＤＨ丢失及ＳＯＤ活性下降的程度均明显低于未用药组。提示该药物对缺血－再灌心肌有保护作用。
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| 关 键 词： | 冠状动脉疾病；疾病模型，动物；3，4－二羟基苯乙酮；心肌；线粒体，心肌；体视学；乳酸脱氢酶类；超氧化 |
EFFECTS OF 3,4,-DIHYDROXYACETOPHENONE(DHAP)ON MYOCARDAL ISCHEMIA-REPERFUSION INJURY OF RABBITS |
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| Cui Xiaoming, Guo Juanxia, Song Huiping, Zeng Qingshan. EFFECTS OF 3,4,-DIHYDROXYACETOPHENONE(DHAP)ON MYOCARDAL ISCHEMIA-REPERFUSION INJURY OF RABBITS[J]. Journal of Central South University. Medical sciences, 1994, 0(1) |
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| Authors: | Cui Xiaoming Guo Juanxia Song Huiping Zeng Qingshan |
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| Affiliation: | Cui Xiaoming, Guo Juanxia, Song Huiping, Zeng Qingshan Department of Histology and Embryology,Hunan Medical University) |
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| Abstract: | he ultrastructural changes together with the activities of LDH and SOD in myocardial tissues were analysed to evaluate the protective effects of DHAP on myocardial ischemia-reperfusion injury of rabbits.The results showed that DHAP could mitigate the myocardialuItrastructural injury and decrease the loss of LDH and the activity drop of SOD. It wassuggested that DHAP had the protective effects on myocardial ischemia-reperfusion injury. |
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