锌酵母的代谢动力学研究

本研究以缺锌大鼠为对象，给予4.6mg／kg体重锌后，观察了血清锌、组织锌的动态变化及24h尿、粪中累计排锌量和锌的吸收率。结果表明，锌酵母进入大鼠体内后血清锌变化的回归方程为：1ogC=0.690-0.041t，生物半衰期（t_(1／2)）为7.4h，消除速度常数K为0.095h~(-1)；锌在组织中均值的变化，除肾脏锌含量在7h达高峰值外，其它脏器中锌含量均在11h达高峰值；锌从尿、粪中24h累计排出量约为给予量的65％，表观吸收率为35.71％。

Research on metabolic kinetics of zinc-enriched yeast

Man-made zinc-deficient mice were used as the objects of study in this research.After zinc-enriched yeast (4.6mg/kg)was given,the authors made observations on the dynamic changes of the zinc content in blood serum and tissues of mice；and zinc excretion and absorpfron in 24 hours.The authors detected that,when zinc-enriched yeast entered the bodies,it caused changes of zinc content in blood serum,at this time,the equation of regression was logC=0.690-0.04lt；the half-life was 7.2 hours；the constant K of eliminating speed was 0.095 hours.The changes of average value of zinc in tissuses were like this：only the zinc content in kidney reached its climax within 7 hours，in other tissues the zinc content reached their climax within the average of 11 hours,The accumulative total of excreted zinc through excrement and urine was about 65% of the given zinc；the absorptivity was 35.17%.