| 尿β_2-微球蛋白对判定环境性镉致肾病的指标意义 |
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| 引用本文： | 蔡诗文 王京京. 尿β_2-微球蛋白对判定环境性镉致肾病的指标意义[J]. 卫生研究, 1994, 23(3): 140-142 |
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| 作者姓名： | 蔡诗文 王京京 |
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| 摘 要： | 根据镉污染区和对照区抽样人群的555名病例对照调查，尿β_2-微球蛋白的正常值为464μg／g肌酐，其镉致肾病早期的判定值为1000μg／g肌酐。此指标的特异度为91％，在配对病例对照中镉接触者肾小管损害的危险性为无接触者的40倍，说明尿β_2-微球蛋白对判定环境性镉致肾病早期具有良好的指标意义。
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| 关 键 词： | 镉接触 镉致肾病 尿β_2-微球蛋白 判定值 |
Significance of urinary β_2-microglobulin as an indicator for discriminating environmental cadmium nephropathy |
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| Cai Shiwen,Wang Jingjing,Shang Qi,Zhu Xueli,et al.. Significance of urinary β_2-microglobulin as an indicator for discriminating environmental cadmium nephropathy[J]. Journal of hygiene research, 1994, 23(3): 140-142 |
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| Authors: | Cai Shiwen Wang Jingjing Shang Qi Zhu Xueli et al. |
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| Abstract: | A case-control study was carried out in a total of 555 sampling cases from the cadmium pollution area and control area.These results demonstrated that normal value of urinary β_2-microglobulin and discriminant value of urinary β_2-microglobulin for early cadmium nephropathy were 464 μg/g Cre and 1000μg/g Cre,re spectively.The specificity of discriminant value was 91%.The risk of renal tubular damage in cases exposed to cadmium was 40 times that of its risk of control in the pairing case-control study.Results of this study in dicate that the urinary β_2-microglobulin is a significant indicator for discriminating environmental cadmium nephropathy in early phase. |
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| Keywords: | Cadmium exposure cadmium nephropathy urinary β_2-microglobulin discriminant value |
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