宣威肺癌的遗传因素初探

运用遗传流行病学的理论和方法，以肺癌病例的配偶做为对照，着重分析了肺癌家族史与宣威肺癌的关系。结果表明，肺癌家族史是肺癌的危险因素之一。既使调整了年龄、性别、吸烟、慢性肺疾患等因素的混杂作用，有肺癌家族史的人患肺癌的危险性仍然是没有肺癌家族史者患肺癌危险性的１．６０倍（Ｐ＜０．０５）。说明了遗传因素在宣威肺癌的发生过程中起着不可忽视的作用。

Analysis of genetic factor on lung cancer in Xuanwei

Using method of genetic epidemiology,and selecting the spouses of lung cancer cases as control group, the relation between the family history of lung cancer patients and lung cancer was analysed. The results declared that the family history was one of lung cancer risk factors. Adjusting the age, sex, smoking and chronic lung diseases and so on, the authors found that there was 1. 60 times greater risk among people with family history of lung cancer (P<0. 05) The genetic factor is to be the risk factor of lung cancer.