| ~(14)C-对硝基酚钠在大鼠体内的吸收、分布和排泄研究 |
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| 引用本文： | 王淑洁 纪云晶. ~(14)C-对硝基酚钠在大鼠体内的吸收、分布和排泄研究[J]. 卫生研究, 1994, 23(3): 133-135 |
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| 作者姓名： | 王淑洁 纪云晶 |
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| 作者单位： | 中国预防医学科学院劳动卫生与职业病研究所!北京100050(王淑洁，李斌)，北京市劳动卫生与职业病防治研究所(纪云晶，粟建林，彭少华) |
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| 摘 要： | 对~(14)C-对硝基酚钠在大鼠体内的吸收、分布和排泄规律研究表明，该化合物易经消化道吸收，迅速分布至全身。其中以肾含量最高，肝、脾次之。染毒后120h，尿、粪、胆汁中放射活性接近本底。~(14)C-对硝基酚钠在大鼠体内的蓄积性很小。
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| 关 键 词： | ~(14)C-对硝基酚钠 毒物代谢动力学 吸收 分布 排泄 |
Study on absorption,distribution and excretion of ~（14）C-p-nitrophenol Sodium in rats |
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| Wang Shujie,Ji Yunjing,Li Jianlin,Li Bin,et al.. Study on absorption,distribution and excretion of ~（14）C-p-nitrophenol Sodium in rats[J]. Journal of hygiene research, 1994, 23(3): 133-135 |
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| Authors: | Wang Shujie Ji Yunjing Li Jianlin Li Bin et al. |
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| Abstract: | The rule of absorption,distribution and excretion of ~(14)C-p-nitrophenol Sodium in rats that this com pound was absorbed through digestive tract easily,then distributed all over the body.The highest content was that in the kidney,and then in the liver and spleen.The radio-activities in the urine,bile and feces reached to the background level at 120 hours after administration.The accumulation of ~(14)C-p-nitropheno Sodium in rats was very low. |
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| Keywords: | ~(14)C-p-nitrophenol Sodium toxicokinetics absorption distribution excretion |
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