Inhibitory effect of antiserum to surface antigen P50 of Babesia gibsoni on growth of parasites in severe combined immunodeficiency mice given canine red blood cells |
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| Authors: | Fukumoto Shinya Xuan Xuenan Takabatake Noriyuki Igarashi Ikuo Sugimoto Chihiro Fujisaki Kozo Nagasawa Hideyuki Mikami Takeshi Suzuki Hiroshi |
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| Affiliation: | National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan. |
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| Abstract: | The inhibitory effect of an antiserum to surface protein P50 of Babesia gibsoni on the growth of the parasite was determined with severe combined immunodeficiency mice given canine red blood cells. The antiserum to the recombinant P50 protein significantly inhibited the parasite growth, indicating that P50 might be a useful vaccine candidate. |
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