Experience of the use of velaxin (venlafaxine) in anxious depression |
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Authors: | N A Il’ina |
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Institution: | (1) Scientific Center for Mental Health, Russian Academy of Medical Sciences, Moscow, Russia |
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Abstract: | Thirty patients (seven men and 23 women, mean age 35.3 ± 7.8 years) with anxious and anxious-apathic depression were studied.
Of these, 24 patients were treated in hospital and six in out-patient clinics. Patients were treated for eight weeks with
venlafaxine at doses of 225–375 mg/day. Mental state was assessed using a series of scales (CGI, HDRS, BDI, HADS-21). A total
of 27 patients (90%) completed treatment. There were 25 (83.3%) responders on the CGI scale: “improvement” in mental state
occurred in 16 (59.3%) of patients and “marked improvement” occurred in nine (33.3%). “Insignificant improvement” was seen
in two cases (7.4%). Complete elimination of symptoms of depression occurred in 33.3% of cases. Velaxin was found to be safe
at intermediate therapeutic doses and there were improvements in laboratory results characterizing patients' somatic status.
Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 108, No. 3, pp. 24–28, March, 2008. |
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Keywords: | velaxin (venlafaxine) treatment anxious depression |
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