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15例中晚期肺癌大剂量顺铂双路化疗并同步放疗的近期疗效观察
引用本文:胡大武 吉林. 15例中晚期肺癌大剂量顺铂双路化疗并同步放疗的近期疗效观察[J]. 中国肿瘤临床, 1996, 23(4): 270-273
作者姓名:胡大武 吉林
作者单位:四川省肿瘤医院影像科,四川省肿瘤医院放疗科
摘    要:作者报告了15例中晚期肺癌经支气管动脉灌注大剂量顺铂(10~150mg)加静脉快速滴注硫代硫酸钠(STS)解毒并行同步放疗的近期疗效观察结果。表明近期有效率CR+PR为93%(14/15),目前全部病例存活。作者认为,大剂量顺铂支气管动脉灌注并同步放疗能明显提高疗效,而使用硫代硫酸钠(STS)解毒和使用基因重组人粒细胞集落刺激因子(rhG-CSF)升白细胞是这种治疗方式得以成功的关键。

关 键 词:肺癌,大剂量顺铂,放射治疗,硫代硫酸钠,基因重组人粒细胞集落刺激因子

Treatment in Advanced Pulmonary Cacinoma by Tworoute High-Does Cisplation Chemotherapy in Combination with Synchronous Radiotherapy A Report of 15 Cases
Hu Da-Wu,Ji Lin,Xu Guo-Hui,et al. Treatment in Advanced Pulmonary Cacinoma by Tworoute High-Does Cisplation Chemotherapy in Combination with Synchronous Radiotherapy A Report of 15 Cases[J]. Chinese Journal of Clinical Oncology, 1996, 23(4): 270-273
Authors:Hu Da-Wu  Ji Lin  Xu Guo-Hui  et al
Abstract:This article reports on the experiences in the treatment of 15 patients with intermediate and late stage pulmonary cancers with high dose cisplatin (100-150mg)perfusion via the bronchial artery plus intavenous sodium thiosuphate(STS)and subcutoneous rhG-CFS in combination with simultaneous radiotherapy.The results showed that effect was seen in 93%of cases. The authors believe that this approach of therapy could improve the terapeutic effect on pulmonary carcinoma.
Keywords:Pulmonary carcinoma High does cisplatin Radiotherapy Sodium theiosulphate rhG-CSF
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