肿瘤患者化疗中托烷司琼与格拉司琼止吐作用的疗效观察

目的:采用托烷司琼和格拉司琼预防肿瘤化疗引起的恶心呕吐,并对其疗效进行观察.方法:将90例恶性肿瘤患者随机分为托烷司琼组和格拉司琼组,每组45例,两组患者均首次接受化疗,观察两组患者恶心、呕吐的程度及治疗效果.结果:托烷司琼组对预防恶性肿瘤化疗所致恶心、呕吐总有效率为75.5%,格拉司琼组总有效率为71.1%,两组疗效基本相似,P>0.05.结论:在肿瘤化疗中,托烷司琼与格拉司琼止吐作用的疗效基本相似,托烷司琼每日用药1次,更为方便.

Curative effect observation of tropisetron and granisetron for treating vomiting in tumor chemotherapy

Objective：To observe the efficacy of tropisetron and granisetron for treating vomiting in tumor chemotherapy.Methods：90 patients with malignant tumors were randomly divided into tropisetron group and granisetron group,45 cases in each group.The patients in two groups received the first chemotherapy.The degree of nausea and vomiting as well as the effects were observed and compared.Results：The curative effective rate was 75.5% in the tropisetron group and 71.1% in the granisetron group,which the effects in the two groups were similar（P0.05）.Conclusion：The antemetic effects of tropisetron and granisetron are basically similar.Tropisetron is taken only once a day with more convenient.