新生儿病理性黄疸1360例病因分析

目的:探讨新生儿病理性黄疸的病因及发病情况.方法:对1360例新生儿病理性黄疸的临床资料进行回顾性分析.结果:10年中新生儿病理性黄疸的发病率呈上升趋势,其主要病因为感染因素423例,占31.10%、围生期因素380例,占27.94%、母乳因素210例,占15.44%、溶血性疾病125例,占9.19%、先天性因素76例,占5.59%、其他原因61例,占4.49%和不明原因85例,占6.25%等.结论:新生儿病理性黄疸的发病率呈每年递增趋势,其主要病因依次为感染因素、围生期因素、母乳因素、溶血性疾病、先天性因素及其他原因.

Pathogenesis analysis of pathologic jaundice in 1360 newborns

Objective：To investigate the pathogenesis of pathological jaundice in newborns and its incidence.Methods：We retrospectively reviewed 1360 newborns with pathologic jaundice treated in our hospital from Jan. 2000 to Dec. 2009, and studied its pathogenesis and incidence of by statistical analysis.Results：The incidence of newborn pathological jaundice had an upgrade tendency in the past ten years.The major pathogenesis included infectious factors （423,31.10%）,perinatal factors （380,27.94%）,factors caused by breast milk （210,15.44%）, hemolytic disease factors （125,9.19%）,inborn factors （76,5.59%）,other causes （61,4.49%） and unknown causes （85,6.25%）.Conclusion：The incidence of newborn pathological jaundice has annually increasing tendency,the major pathogenesis includes infectious factors,perinatal factors,factors caused by breast milk,hemolytic disease factors,inborn factors,other causes and unknown causes.