厄贝沙坦联合贝那普利治疗糖尿病肾病疗效观察

目的:探讨厄贝沙坦联合贝那普利治疗糖尿病肾病的临床疗效。方法:将72例2型糖尿病肾病患者分为两组,分别采用单一贝那普利和贝那普利联合厄贝沙坦两种方法治疗,观察两组疗效。结果:两组UAER、SBP、DBP均有所下降,和对照组比较,治疗组UAER下降更加明显,组内和组间比较差异均有显著性(P<0.05)。两组治疗过程中均未出现明显不良反应。结论:厄贝沙坦联合贝那普利治疗糖尿病肾病可明显降低尿蛋白、控制血压、提高疗效。

Clinical Efficacy Analysis of Irbesartan Combined with Benazepril in Treatment of Diabetic Nephropathy

Objective:To investigate the clinical efficacy of irbesartan combined with benazepril in treatment of diabetic nephropathy.Methods:72 cases of 2 type diabetic nephropathy were divided into two groups,treated with single benazepril or benazepril combined with irbesartan,the efficacy of the two groups were observed.Results:Both UAER,SBP and DBP in two groups were decreased,and compared with control group,UAER in treatment group decreased more significantly(P<0.05).There were no obvious adverse reactions in two groups.Conclusion:Using irbesartan combined with benazepril in treatment of diabetic nephropathy could significantly reduce urinary protein,control blood pressure and improve the outcome.