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帕罗西汀治疗伴躯体症状抑郁对照研究
引用本文:王爱荣,张秀贞,张仲荣. 帕罗西汀治疗伴躯体症状抑郁对照研究[J]. 精神医学杂志, 2007, 20(2): 93-94
作者姓名:王爱荣  张秀贞  张仲荣
作者单位:山东省济宁市精神病防治院,山东省济宁市精神病防治院,山东省济宁市精神病防治院
摘    要:目的探讨帕罗西汀治疗伴躯体症状抑郁症的疗效及安全性。方法将80例伴躯体症状的抑郁症患者随机分为阿米替林组40例,帕罗西汀组40例,共治疗6周,采用汉米尔顿抑郁量表(HAMD)和临床总体评定量表(CGI)评定临床疗效,采用副反应量表(TESS)评定副反应。结果帕罗西汀组与阿米替林组治疗前后HAMD和CGI-SI分值比较均有显著性差异,而两组减分相比治疗前后无显著性差异,帕罗西汀组副作用明显比阿米替林组小,服用方便,依从性好。结论帕罗西汀是治疗伴躯体症状抑郁症的理想药物。

关 键 词:伴躯体症状抑郁症  帕罗西汀  阿米替林
文章编号:1009-7201(2007)-02-0093-02
收稿时间:2006-11-03
修稿时间:2006-11-03

A comparative of study paroxetine in the treatment of depression with physical symptoms
WANG Ai-rong,ZHANG Xiu-zhen,ZHANG Zhong-rong. A comparative of study paroxetine in the treatment of depression with physical symptoms[J]. Journal of Psychiatry, 2007, 20(2): 93-94
Authors:WANG Ai-rong  ZHANG Xiu-zhen  ZHANG Zhong-rong
Affiliation:Mental Hospital of J ining, Shandong 272051, China
Abstract:Objective To study the effect and safty of paroxetine in the treatment of depression with physical symptoms.Methods A total of 80 depressive patients were divided into control group treated by amitriptyline and study group treated by paroxetine for 6 weeks of treatment.The effect was evaluated with HAMD and CGI and the adverse effects were evaluated with TESS.Results Scores of HAMD and CGI-SI had significant differences before and after treatment in two groups,but the difference between two groups was not found in decreased scores.Conclusion Paroxetine is effective for depression with physical symptoms.
Keywords:Depression physical symptom Paroxetine Amitriptyline
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