Mixed glioneuronal tumor: A dysembryoplastic neuroepithelial tumor with rosette‐forming glioneuronal tumor component

Neuronal and mixed neuronal‐glial tumors of the CNS show a wide spectrum of components. Here, we report an unusual case of brain tumor with combined histological features of dysembryoplastic neuroepithelial tumor (DNT) and rosette‐forming glioneuronal tumor (RGNT) in a 23‐year‐old man. It arose in the left anterior cingulate cortex with a pseudo‐polycystic appearance on neuroimaging. Histological features contained the “specific glioneuronal element” mimicking DNT and the components of distinct neurocytic rosettes with a center of neuropil islands and pilocytic astrocytoma resembling RGNT. Although the mechanisms of mixed glioneuronal tumor are far from being well‐known, their co‐existence might suggest a possible etiologic relationship between DNT and RGNT.