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Crystal structure and enzymatic activity of an ADAMTS‐13 mutant with the East Asian‐specific P475S polymorphism |
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| Authors: | M. Akiyama D. Nakayama S. Takeda K. Kokame J. Takagi T. Miyata |
| Affiliation: | 1. Department of Molecular Pathogenesis, National Cerebral and Cardiovascular Center, , Osaka, Japan;2. Department of Cardiac Physiology, National Cerebral and Cardiovascular Center, , Osaka, Japan;3. Laboratory of Protein Synthesis and Expression, Institute for Protein Research, Osaka University, , Osaka, Japan |
| Abstract: | |
| Keywords: | ADAMTS‐13 crystallography genetic polymorphism human proteins thrombotic thrombocytopenic purpura von Willebrand factor |