重度广泛型侵袭性牙周炎患者牙周序列治疗的临床研究

目的：观察重度广泛型侵袭性牙周炎（generalized aggressive periodontitis, GAgP）患者牙周序列治疗后临床指标的变化，并评价其治疗效果。方法：15例GAgP患者在龈上洁治后1个月内完成龈下刮治、根面平整及光动力治疗，刮治后4周再评估，行翻瓣及翻瓣植骨术，每3个月进行1次牙周维护，序列治疗后纵向观察12个月。在基线和维护期各时间点记录全口探诊深度（probing depth，PD）、探诊出血（bleeding on probing, BOP）和牙齿松动度，磨牙记录根分叉病变的程度。结果：在基线时患者平均PD（3．96±2．21）mm，BOP阳性位点占88．1％。序列治疗后12个月平均PD（2．36±1．28）mm，BOP阳性位点减少至8．7％，其中轻、中、重度位点治疗后PD值与治疗前比较差异有统计学意义（P〈0．05）。结论：GAgP患者经牙周序列治疗和定期牙周维护能取得良好的治疗效果。

Clinical effects of periodontal-sequence treatment on severe generalized aggressive periodontitis

Objective： To investigate the clinical results of periodontal-sequence treatment of generalized aggressive periodontitis in a Chinese population. Method： Fifteen patients aged （24.6±4.0）years with generalized aggressive periodontitis were included in this prospective study. All subjects received scaling and root planing and photodynamic therapy （PDT）, re-evaluation after four weeks, as the case for flap surgery or bone graft, clinically monitored every 3months for 12 months. The clinical parameters, including probing depth （PD）, bleeding on probing （BOP） and mobility, furcation involvement of molars were recorded at baseline,3,6,9 and 12 months after treatment. Result：At baseline,the mean PD of patients was （3.96±2.21） mm,the percentage of BOP positive sites was 88.1%. At 12 months after surgery,the mean pocket depth reduction was 1.6 mm, the percentage of BOP positive sites reduced to 8.7 %. There was a statistically significant decrease of mild, moderate and severe sites the PD after treatment （P 〈0.05）. Conclusion： Periodontal-sequence treatment is effective for the generalized aggressive periodontitis and every 3 months SPT is necessary for maintenance.