| 在翼状胬肉手术中应用自体角膜缘干细胞移植联合丝裂霉素C的疗效观察 |
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| 引用本文： | 杨云良,仝佳.在翼状胬肉手术中应用自体角膜缘干细胞移植联合丝裂霉素C的疗效观察[J].江苏大学学报(医学版),2005,15(6):494-495. |
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| 作者姓名： | 杨云良 仝佳 |
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| 作者单位： | 江苏大学附属医院眼科;江苏大学医学技术学院免疫教研室 |
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| 基金项目： | 江苏大学校基金资助项目(JDQ03027) |
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| 摘 要： | 目的：评价自体角膜缘干细胞移植联合丝裂霉素C在翼状胬肉治疗中的临床疗效。方法：A组37例（48只眼）翼状胬肉（其中11例为复发性翼状胬肉）在手术显微镜下实施翼状胬肉常规切除联合丝裂霉素C（MMC）的治疗，然后行自体角膜缘干细胞移植。并与对照组B组35例（43只眼）行胬肉切除联合球结膜移植的病例比较。结果：随访4-26个月，门诊复诊A组未发现复发者，B组发现4例复发者。结论：自体角膜缘干细胞移植联合丝裂霉素C治疗翼状胬肉具有手术操作简单易行、安全可靠、术后复发率低等优点，是一种较为可行的临床治疗方法。
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| 关 键 词： | 翼状胬肉 手术 角膜缘干细胞 丝裂霉素 |
| 文章编号： | 1671-7783(2005)06-0494-02 |
| 修稿时间： | 2005年9月15日 |
Autologous Stem Cells Transplantation of Limbus Corneae Combining Mitomycin C to Treat Pterygium |
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| YANG Yun-liang,TONG Jia.Autologous Stem Cells Transplantation of Limbus Corneae Combining Mitomycin C to Treat Pterygium[J].Journal of Jiangsu University Medicine Edition,2005,15(6):494-495. |
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| Authors: | YANG Yun-liang TONG Jia |
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| Affiliation: | YANG Yun-liang~1,TONG Jia~2 |
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| Abstract: | Objective: To observe autologous stem cells transplantation of limbus corneae combining mitomycin C to treat pterygium.Methods: Group A,37 cases(48 eyes)(including 11 recurrent pterygiums) were operated with pterygium excision,combining mitomycin C,followed with autologous stem cells transplantation of limbus corneae;the control group B,35 cases(43eyes) were operated with pterygium excision only,combining transplantation of bulbar conjunctiva.Result:Following up 4-26 months,we discovered Group A had no recurrent case and Group B had four recurrent cases.Conclusion: Autologous stem cells transplantation of limbus corneae combining mitomycin C to treat pterygium was an easy,safe,effective method with low recurrence. |
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| Keywords: | Pterygium Operation Stem cells of limbus corneae Mitomycin C |
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