44例结直肠癌合并恶性胸腹腔积液患者的预后分析

目的探讨结直肠癌合并恶性胸腹腔积液的预后因素。方法回顾性分析2001年1月至2010年12月中国医学科学院肿瘤医院内科结直肠癌合并恶性胸腹腔积液患者的临床资料。结果 44例患者中,治疗后积液完全消失2例,减少16例,稳定6例,增多20例。中位总生存时间为8个月。单因素分析结果显示,KPS评分、肝转移、治疗模式、积液控制率、白蛋白以及胆红素水平与总生存时间有关。结论 KPS评分≥80分、无肝转移、全身化疗、积液控制好、白蛋白和胆红素水平正常的患者预后更好。

Prognostic factors in 44 colorectal cancer patients with malignant pleural effusion and/or ascites

Objective To explore prognostic factors in patients with colorectal cancer combined malignant pleural effusion and/or ascites.Methods Clinical data of colorectal cancer patients with malignant pleural effusion and/or ascites in our hospital from January 2001 to December 2010 were analyzed retrospectively.Results The median survival time was 8 months for all the 44 patients.2 patients with disappearance of effusion,16 with decrease of effusion,6 with no change of effusion and 20 with increase of effusion.Univariate analysis showed that performance status,treatment methods,status of liver metastases,the control of effusions,albumin,bilirubin were prognostic factors.Conclusion KPS≥80,combined with systemic chemotherapy,without liver metastases,better control of effusions,normal level of albumin and bilirubin seem have a better prognosis.