| 68例狼疮肾炎的肾小管间质病变探讨 |
| |
| 引用本文： | 王均玉,李幼姬,叶任高.68例狼疮肾炎的肾小管间质病变探讨[J].中华肾脏病杂志,1999,0(2):82-85. |
| |
| 作者姓名： | 王均玉 李幼姬 叶任高 |
| |
| 作者单位： | 中山医科大学附属第一医院肾内科 |
| |
| 摘 要： | 目的探讨肾小管间质病变（ＴＩＬ）在狼疮肾炎（ＬＮ）的意义。方法分析了６８例ＬＮ资料，并对其中４２例作了较长期的随访。结果ＬＮ的ＴＩＬ发生率为７５％，ＴＩＬ明显者，肾小管功能显著下降，血肌酐、尿蛋白水平明显增加（Ｐ＜００１），肾小管间质与肾小球急、慢性病理改变之间均显著相关（Ｐ＜００１），同时，存在明显ＴＩＬ者，其生存率及肾存活率有下降趋势。结论ＴＩＬ与肾小球病变呈平行的正相关关系，且对ＬＮ预后有一定的影响。
|
| 关 键 词： | 狼疮肾炎 肾小管间质病变 临床病理 |
Analysis of tubulointerstitial lesions in 68 lupus nephritis |
| |
| WANG Junyu,LI Youji,YE
Rengao.Analysis of tubulointerstitial lesions in 68 lupus nephritis[J].Chinese Journal of Nephrology,1999,0(2):82-85. |
| |
| Authors: | WANG Junyu LI Youji YE
Rengao |
| |
| Institution: | WANG Junyu,LI Youji,YE
Rengao.Department of Nephrology,the First Affiliated Hospital,Sun Yatset University of Medical
Sciences,Guangzhou 510080 |
| |
| Abstract: | Objective To investigate the relationships between
tubulointerstitial lesions(TIL) and clinics and prognosis in lupus nephritis(LN). Methods 68 LN
cases were reviewed and 42 cases among them were followed up. Result The incidence of TIL
in LN was 75%,and patients with severe TIL had significantly decreased tubular function and
higher mean Scr concentration and proteinuria(P<001).TIL was closely correlated to glomerular
damages(P<001).Meanwhile patients with severe TIL had decreased survival and renal
survival. ConclusionTIL can affect the clinic and prognosis of LN,and is positively correlated to
glomerular lesions. |
| |
| Keywords: | Lupus nephritisTubulointerstitial lesionsClinicopathology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
