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Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein
Authors:Hsu Jocelyn C  Dev Anurupa  Wing Aimee  Brew Christine T  Bjeldanes Leonard F  Firestone Gary L
Affiliation:Department of Molecular and Cell Biology and The Cancer Research Laboratory, The University of California at Berkeley, Berkeley, CA 94720, USA.
Abstract:
Keywords:I3C, indole-3-carbinol   DIM, 3,3′-diindolylmethane   TRYP, tryptophol   LNCaP, Lymph node carcinoma of the prostate   CDK, cyclin-dependent kinase   CKI, cyclin-dependent kinase inhibitor   ser, serine   siRNA, short interfering RNA   RNAi, RNA interference
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