| 电磁场生物效应的细胞膜及蛋白激酶信号转导机制研究 |
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| 引用本文： | 孙文均,姜槐.电磁场生物效应的细胞膜及蛋白激酶信号转导机制研究[J].国际生物医学工程杂志,2004,27(5):260-263. |
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| 作者姓名： | 孙文均 姜槐 |
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| 作者单位： | 杭州,浙江大学医学院生物电磁学实验室,310031;杭州,浙江大学医学院生物电磁学实验室,310031 |
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| 基金项目： | 国家自然科学基金资助项目(30100036)，浙江省自然科学基金资助项目(301065) |
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| 摘 要： | 环境中低强度的电磁场通常通过细胞膜将物理信号转化成生物信号,进而经细胞内信号 转导途径,尤其是蛋白激酶相关途径进行传递,最终产生生物效应的模式是可能的作用机制,也是目前 生物电磁学研究的热点之一。本文就电磁场与细胞膜及蛋白激酶相关的信号转导的研究作了综述。
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| 关 键 词： | 电磁场 信号转导 细胞膜 蛋白激酶 |
| 文章编号： | 1001-1110(2004)05-0260-04 |
| 修稿时间： | 2004年1月14日 |
The study on biological effects mechanism of cellular membrane and protein kinase signal transduction induced by electromagnetic field |
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| SUN Wen-jun,JIANG Huai . Bioelectromagnetics Lab,Zhejiang University School of Medicine,Hangzhou ,China.The study on biological effects mechanism of cellular membrane and protein kinase signal transduction induced by electromagnetic field[J].International Journal of Biomedical Engineering,2004,27(5):260-263. |
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| Authors: | SUN Wen-jun JIANG Huai Bioelectromagnetics Lab Zhejiang University School of Medicine Hangzhou China |
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| Institution: | SUN Wen-jun,JIANG Huai . Bioelectromagnetics Lab,Zhejiang University School of Medicine,Hangzhou 310031,China |
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| Abstract: | It is the possible interactive mechanism that the electromagnetic field in our environment with low energy may modify the cell membrane and transfer physical signal into biological signal, then transduct the signal into cell via signal transduction pathways, especially the protein kinase related pathways, and finally produce the biological effects. The studies on mechanism of the signal transduction of electromagnetic field also become the hotpoint in electromagnetics domain. This article reviewed the advance in the study of interactive mechanism between electromagnetic field factor with cellular membrane and protein kinase signal transduction pathways. |
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| Keywords: | electromagnetic field signal transduction cellular membrane protein kinase |
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