| 山莨菪硷对家兔急性实验性血清病的免疫调节作用 |
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| 引用本文： | 封莉莉,朱锡华.山莨菪硷对家兔急性实验性血清病的免疫调节作用[J].第三军医大学学报,1988(3). |
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| 作者姓名： | 封莉莉 朱锡华 |
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| 作者单位： | 第三军医大学免疫学教研室
(封莉莉)，第三军医大学免疫学教研室(朱锡华) |
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| 摘 要： | 本实验用山莨菪硷(654-2)处理急性实验性血清病家兔(AESSR),探讨了654-2对急性实验性血清病(AESS)的免疫调节作用。实验结果表明,654-2可降低循环中特异性抗体水平,减少特异性免疫复合物(IC)量,抑制血浆中组织蛋白酶D(Cath-D)活性,使补体水平下降不明显,并减轻肾脏病变程度。
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| 关 键 词： | 山莨菪硷(654-2)-兔疫学 山莨菪硷(654-2)-药效学 血清病-实验研究 肾脏疾病-免疫疗法 |
The Immunomodulatory Effects of Anisodamine on Rabbits with Acute Experimental Serum Sickness |
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| Feng Lily and Zhu Xihua.The Immunomodulatory Effects of Anisodamine on Rabbits with Acute Experimental Serum Sickness[J].Acta Academiae Medicinae Militaris Tertiae,1988(3). |
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| Authors: | Feng Lily and Zhu Xihua |
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| Abstract: | Anisodamine (654-2) was administered to rabbits with acute experimental serum sickness (AESS) to study the immunomodulatory effects of 654-2 on AESS. The results suggested that 654-2 may decrease the serum specific antibody and immune complex (IC), inhibit the activity of serum cathepsin D (Cath-D), make the level of complemnts in narrow change, and improved the renal injury. |
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| Keywords: | Anisodamine(654-2)/immunology Anisodamine(654-2)/pharmacody-namics Serum sickness/experimental study Kidney diseases/immunotharapy serum sickness |
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