克林霉素联合妇科千金胶囊治疗慢性盆腔炎的疗效及对血清C反应蛋白的影响

目的探讨克林霉素联合妇科千金胶囊治疗慢性盆腔炎(chronic pelvic inflammatory disease,CPID)的疗效及对血清C反应蛋白(C-reactive protein,CRP)的影响。方法将92例CPID患者随机分为观察组和对照组,每组各46例。观察组予克林霉素盐酸盐注射液、妇科千金胶囊治疗;对照组予青霉素钠、甲硝唑片治疗。比较两组患者疗效、临床症状积分的变化、CRP的变化及复发率。结果观察组总有效率97.83%,高于对照组73.91%(P0.05);两组患者治疗后的临床症状积分、血清CRP均低于治疗前,且观察组降低更显著(P0.05);观察组的复发率为4.35%,低于对照组19.57%(P0.05)。结论克林霉素联合妇科千金胶囊可以提高对CPID的疗效,有效抑制炎症反应,迅速改善临床症状,安全性好,复发率低。

Clinical effects of Clindamycin combined with gynecology Qianjin capsules in the treatment of chronic pelvic inflammatory and the impact on serum C - reactive protein

Objective To investigate the effect of Clindamycin combined with gynecology Qianjin capsules in treatment of chronic pelvic inflammatory,and to explore its impact on serum C - reactive protein（CRP）. Methods 92 patients with chronic pelvic inflammatory were randomly divided into observation group and control group,46 cases in each group. The cases in observation group were given Clindamycin hydrochloride injection and Qianjin capsules, while cases in control group were given penicillin sodium and Metronidazole tablets. Clinical efficacy,clinical symptom score,changes of CRp and recurrence rate of two groups were compared. Results The total effective rate of observation group was 97. 83% ,which was significantly higher than control group（73. 91% ）（P〈 0. 05）;The clinical symptom score of two groups were significantly lower than that before treatment. clinical symptom score of observation group reduced more significantly（P〈 0. 05）;Serum CRP levels of two groups were significantly lower than that before treatment,CRP levels of observation group decreased more significantly（P〈 0. 05）;The recurrence rate of observation group was 4. 35% ,which was significantly lower than control group（P〈 0. 05）. Conclusion Clindamycin combined gynecology Qianjin capsules in treatment of chronic pelvic inflammatory can enhance the effectiveness,inhibit inflammation,rapid the improvement of clinical symptoms with safety and low recurrence rate.