持续泵注与多次注药法用于硬膜外麻醉比较性研究

目的：观察微量泵持续输注法与分次注药法用于硬膜外麻醉的麻醉效果比较。方法：60例骨科下肢手术患者随机分为两组，微量泵持续输注组（A组）和常规分次注药组（B组），每组30例，硬膜外用药均为2％利多卡因先注入实验量3ml,观察5min，无全脊麻征象后，A组以0．13—0．15ml·kg^-1·h^-1速度持续输注药物至手术结束；B组10—12ml，2—3min内分次注完，术中未再追加药物。观察镇痛起效时间、麻醉平面、镇痛效果、运动阻滞程度、BP、HR、SPO2和用药总量。结果：麻醉平面、镇痛效果、运动阻滞程度、SPO2两组间差异无显著性（P〉0．05）。A组用药总量显著减少（P〈0．01）BP波动显著降低（P〈0．01）。结论：微量泵持续输注法与分次注药法用于硬膜外麻醉比较麻醉效果可靠，BP平稳，用药量少。

Comparative sthdy on continuous pump infusion and several times infusion undergoing epidural anesthesia

Objective：To compare the result of continuous pump infusion and several times infusion undergoing epidural anesthesia. Methods： Sixty patients scheduled for lower limbs surgery were randomly divided into groups A and B with 30 cases each. A is continuous infusion group, B is several times infusion group. Epidural puncter and catheterization were carried routinely, continue infusign drugs to the end of the operation with speed 0.13 - 0.15ml kg^-1 h^-1 in group A and infuse drug 10 - 12ml in 2 - 3 minutes in group B. To observe analgesia effect, motor nerve blockade BP, HR, SPO2, and the total dose of drugs. Results：There were nosignificant differences between two groups in anesthesia level,analgesia effect,motor nerve blcockade and SPO2（P 〉 0.05）.The total dose of drugs and BP fluctuation were significant reduced. （ P 〈 0.01）. Conclusions： Continuous pump infusion on epidural anesthesia has the advantage of better analgesia, stable BP. and less anesthetic drugs.