不同途径营养支持治疗急性重症胰腺炎的效果

目的探讨急性重症胰腺炎（SAP）患者早期给予肠内营养（EN）或肠外营养（PN）的治疗效果及护理。方法将44例SAP患者分为研究组23例和对照组21例。研究组早期给予EN，对照组给予PN至进食。每周监测血清淀粉酶和白蛋白水平，比较并发症、感染率、病死率及住院费用。结果两组血清淀粉酶和白蛋白在治疗第1周差异均无统计学意义，第2周两组血清淀粉酶均较第1周下降，白蛋白均较第1周上升，但研究组下降或上升的水平较对照组高，差异有统计学意义；研究组的并发症、感染率及平均住院费用均低于对照组，差异有统计学意义。结论SAP患者早期给予EN，可减少相关并发症的发生，减少住院费用；给予合理营养配方，掌握正确的输注方法，做好各项护理是早期给予EN的重要保证。

Effect of nutrition supports via different routes in treatment of patients having severe acute pancreatitis

Objective To investigate the therapeutic effects and nursing emphases for patients with severe acute pancreatitis (SAP) by providing enteral nutrition (EN) or parenteral nutrition (PN) during the early stage of the disease.Methods 44 cases of SAP patients were divided into two groups,with the research group having 23 patients and the control group having 21 patients.The research group began with enteral nutrition (EN) after having been enrolled in hospital during the early state of the disease,while the control group was practised with parenteral nutrition (PN) before giving the routine enteral alimentation.Serum amylase and albumin levels were detected weekly.And complications,infection rate,mortality rate and cost in hospical were compared between two groups.Results Serum amylase and albumin levels of both groups did not show s statistical difference during the first week of treatment.And in the second week of treatment,serum amylase levels of both groups had a decrease in view of that in the first week,and serum albumin level of both groups increased in view of that in the first week.But,the change,whether it is a decrease or an increase,for the research group,is larger than the corresponding change of the control group,and the change shows a statistical significance.Complications,infection rate and average cost spending in hospital residing of the research group were less than those of the control group,and the difference is significant in statistics.Conclusions Application of early enteral nutrition (EN) in severe acute psncreatitis (SAP) patients can reduce the occurrence of the relevant complications,and hospital-residing cost.Giving appropriate compounding of nutritions,mastering correct method for conducting transfusion,and doing well all the items of nursing,are important guarantees for fulfilling early enteral nutrition (EN) in severe acute pancreatitis patients.