| 癫痫病人丙戊酸钠血浓度监测及其临床应用 |
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| 引用本文： | 张敬军,俞丽云.癫痫病人丙戊酸钠血浓度监测及其临床应用[J].中国临床神经科学,1995,3(1):14-18. |
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| 作者姓名： | 张敬军 俞丽云 |
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| 作者单位： | 上海医科大学华山医院神经科，上海医科大学华山医院神经科，上海医科大学华山医院神经科，上海医科大学华山医院神经科 研究生 200040 现在山东省泰山医学院神经科，200040，200040，200040 |
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| 摘 要： | 本文报告丙戊酸钠治疗各型癫痫122例,丙戊酸钠治疗各型癫痫的有效率为83％。多数患者的有效血浓度范围为30～120μg/ml,有效剂量为10～60mg/kg·d,对癫痫患者,应据其临床发作情况,有无药物不良反应,参考丙戊酸钠血浓度调整剂量。
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| 关 键 词： | 癫痫 丙戊酸钠 血浓度 |
Measurement of Serum Sodium Valproate Concentration and Clinical Application in the Patients With Epilepsy |
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| Zhang Jing-Jun,Yu Li-Yun,Qu Zhi-Ping,Hong Zhen.Measurement of Serum Sodium Valproate Concentration and Clinical Application in the Patients With Epilepsy[J].Chinese Journal of Clinical Neurosciences,1995,3(1):14-18. |
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| Authors: | Zhang Jing-Jun Yu Li-Yun Qu Zhi-Ping Hong Zhen |
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| Institution: | Zhang Jing-Jun,Yu Li-Yun,Qu Zhi-Ping,Hong Zhen Department of Neurology,Huashan Hospital,Shanghai Medical University,Shanghai 200040 |
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| Abstract: | This paper reports 122 cases of various types of epilepsy who were treated with sodium valproate and the measurement of its serum concentration. In clinics, the rate of effective cure for various types of epilepsy with sodium valproate is 83%. The effective serum concentrations and effective daily dose in most patients are 30-120;ig/ml and 10-60mg/kg d respectively. It is recommended that the dosage must be regulated, according to the clinical state and the appearance of drug side-effect, in addition, the levels of serum sodium valproate concentration. |
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| Keywords: | Epilepsy Sodium valproate Serum concentration |
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