不同浓度的阿奇霉素在不同载体中的稳定性考察

目的比较阿奇霉素在不同载体中的稳定性,并同时考察在同一种载体中,当阿奇霉素处于不同浓度时的稳定性是否相同,以验证高浓度的阿奇霉素输液比低浓度的阿奇霉素输液滴速快的理论。方法在25℃条件下将注射用阿奇霉素分别与0.9%氯化钠注射液（0.9%NS）、5%葡萄糖注射液（5%GS）、5%葡萄糖氯化钠注射液（5%GNS）配伍后,于6h内的各个不同时间点（0h、0.25h、0.5h、1h、2h、3h、4h、6h）测定含量变化。结果高浓度的阿奇霉素输液的稳定性比低浓度的阿奇霉素输液差。

The test for the stability of different concentrations of Azithromycin injection with different infusions

OBJECTIVE To study the stability of azithromycin injection in different infusions and the different concentrations in the same infusions,to confirma the high concentration should be used more speedy than the low.METHODS At 25℃,let azithromycin injection was mixed with 0.9% saline infusion(0.9%NS),5% glucose infusions(5%GS),5% glucose saline infusions.Determine the content of azithromycin by UV-2401PC at the different time points(0h、0.25h、0.5h、1h、2h、3h、4h、6h)in 6h.RESULTS The stability of the high concentration of azithromycin injection is lower than the low′s.