IgE receptors |
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Authors: | Natalija Novak Stefan Kraft Thomas Bieber |
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Affiliation: | Department of Dermatology, Friedrich-Wilhelms-University of Bonn, D-53105, Bonn, Germany. |
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Abstract: | IgE receptors are implicated as important components of the immunological pathway in allergic and inflammatory diseases. Recent investigations have begun to unravel the structure, signal transduction and function of IgE receptors from different cell types in rodent and human systems. Studies of the mechanisms involved might provide opportunities for therapeutic intervention strategies in the treatment of allergic and hypersensitivity reactions. |
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Keywords: | allergy inflammation IgE FceRI FceRII signal transduction therapy |
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