The role of testosterone in the feedback control of male FSH and LH secretion |
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| Authors: | G. Börsch J. Mauss E. Richter K. Bormacher G. Leyendecker W. Nocke |
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| Affiliation: | (1) Universitäts-Hautklinik und Poliklinik der Gesamthochschule, Essen;(2) Klinische Forschung der Schering AG, Berlin;(3) Abteilung für Gynäkologische Encokrinologie der Universitäts-Frauenklinik, Bonn-Venusberg |
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| Abstract: | Summary Intramuscular administration of 250 mg testosterone oenanthate per week over a period of 21 weeks treatment rapidly and sustainedly suppressed serum LH as well as FSH levels in seven normal males, while serum testosterone rose by a factor of approximately two. These together with other data provide increasing evidence for a feedback control of FSH secretion by gonadal steroids in the male in addition to the already described but as yet undefined tubular testicular factor. |
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| Keywords: | FSH LH testosterone gonadotropin regulation |
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