Effects of thyroxine and 1-methyl, 2-mercaptoimidazol on phosphoinositides synthesis in rat liver |
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| Authors: | Nataliya A Babenko and Oksana A Krasilnikova |
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| Institution: | (1) Department of Physiology of Ontogenesis, Institute of Biology, Karazin Kharkov National University, 4, Svobody pl, 61077 Kharkov, Ukraine |
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| Abstract: | Background Phosphoinositides mediate one of the intracellular signal transduction pathways and produce a class of second messengers that
are involved in the action of hormones and neurotransmitters on target cells. Thyroid hormones are well known regulators of
lipid metabolism and modulators of signal transduction in cells. However, little is known about phosphoinositides cycle regulation
by thyroid hormones. The present paper deals with phosphoinositides synthesis de novo and acylation in liver at different
thyroid status of rats. |
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