曲安奈德在尿道内切开术治疗尿道狭窄的疗效研究

目的探讨曲安奈德在尿道内切开术治疗尿道狭窄的临床疗效。方法将该院2011年6月至2012年6月收治的58例男性尿道狭窄患者分为2组,每组各29例,对照组单纯行尿道内切开术,观察组在对照组基础上加用曲安奈德瘢痕内注射,比较2组临床治疗效果。结果观察组治疗后最大尿流量（Qmax）和狭窄段内径分别为（20.77±1.12）mL/s和（4.65±0.34）mm,均较治疗前和对照组显著增加,差异有统计学意义（P〈0.05）;观察组术后6个月和1年的复发率分别为7.14%和12.56%,均明显低于对照组的23.21%和33.93%,差异有统计学意义（P〈0.05）。结论尿道内切开术治疗尿道狭窄创伤小、并发症少,安全、有效,且联合曲安奈德瘢痕内注射可延缓病情复发,具有较好的临床应用价值。

The efficacy verify of triamcinolone acetonide treating urethral stricture by urethrotomy

Objective To explore the efficacy Verify of triamcinolone acetonide in the treatment of urethral stricture by urethrotomy .Methods 58 cases of male urethral stricture in our hospital from June 2011 to June 2012 were randomly divided into the control group and the observation group ,29 cases in each group .The control group was given urethrotomy while the observation group was given triamcinolone acetonide injection on the basis of the control group ,and the clinical outcomes were compared between two groups .Results After treatment ,the Qmax and diameter stenosis of the observation gorup were （20 .77 ＆#177; 1 .12）mL/s and （4 .65 ＆#177; 0 .34）mm ,which were significantly higher than before treatment and the control group（P〈0 .05） ,after 6 month and 1-year ,the recurrence rates of the observation group were 7 .14% and 12 .56% ,which were significantly lower than those of the control group（23 .21%and 33 .93% ）（P〈0 .05） .Conclusion Urethrotomy in treatment of urethral stricture was smaller trauma ,fewer com-plications ,safe and effective ,and intravitreal triamcinolone injection scar can delay relapse ,which has better clinical value .