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输血对重型颅脑损伤患者凝血功能的影响
引用本文:戴大鹏,孙晓阳.输血对重型颅脑损伤患者凝血功能的影响[J].检验医学与临床,2014,0(11):1474-1475.
作者姓名:戴大鹏  孙晓阳
作者单位:戴大鹏 (南京医科大学附属淮安第一医院,江苏淮安,223300); 孙晓阳 (江苏省淮安市第一人民医院 223300);
摘    要:目的 探讨输血速度及输血量对重型颅脑损伤患者凝血功能的影响。方法 对该院60例重型颅脑损伤患者输血前、后凝血功能指标进行检测并对比分析。结果 重型颅脑损伤患者输血后凝血酶原时间(PT )、活化部分凝血酶原时间(APTT)、凝血酶时间(TT)显著增加,并且输血速度较快、输血量较大的患者凝血功能指标的改变更加明显。结论 重型颅脑损伤患者输血速度较快、输血量较大会加重患者的凝血障碍,应及时补充血浆,以改善其凝血功能,提高临床输血疗效。

关 键 词:重型颅脑损伤  输血  凝血指标

Coagulation function changes in patients with severe brain injury after blood transfusion
DAI Da-peng,SUN Xiao-yang.Coagulation function changes in patients with severe brain injury after blood transfusion[J].Laboratory Medicine and Clinic,2014,0(11):1474-1475.
Authors:DAI Da-peng  SUN Xiao-yang
Institution:1. The Huai'an First Hospital Affiliated with Nanjing Medical University, Huai'an , 223300, China ; 2. The Huai'an First people's Hospital , Huai'an ,223300,China)
Abstract:Objective To investigate the coagulation function changes with different speed and different volume of blood transfusion in patients with severe traumatic brain injury .Methods Coagulation parameters of 60 patients with severe traumatic brain injury were detected and analyzed before and after blood transfusion .Results prothrombin time ,activated partial thromboplastin time ,thrombin time was significantly changed in patients with severe traumatic brain injury after transfusion while patients with faster and more blood transfusion ,changed more pronounced .Conclusion Inappropriate speed and volume of blood transfusion in patients with severe traumatic brain injury will deteriorate coagulation dysfunction ,plasma should be promptly added to improve its coagulation function and blood transfusion efficacy .
Keywords:severe traumatic brain injury  blood transfusion  coagulation indicator
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