| 多波长系数法测定复方氯霉素醇溶液中3组分的含量 |
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| 引用本文： | 缪春辉,冷瑷国,涂飞龙. 多波长系数法测定复方氯霉素醇溶液中3组分的含量[J]. 中国药房, 2003, 14(3): 177-178 |
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| 作者姓名： | 缪春辉 冷瑷国 涂飞龙 |
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| 作者单位： | 解放军第92医院药械科,福建南平市,353000 |
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| 摘 要： | 目的 :建立不经分离同时测定复方氯霉素醇溶液中氯霉素、水杨酸、甲硝唑含量的方法。方法 :采用多波长系数法测定3主药的含量 ,测定波长分别为277 5、297 0、317 0nm。结果 :平均回收率氯霉素、水杨酸、甲硝唑分别为 (100 22±0 74) %、(99 25±1 54) %、(99 79±1 92) %。结论 :该方法简便、快速、准确 ,适用于医院中多组分制剂的常规分析。
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| 关 键 词： | 复方氯霉素醇溶液 多波长系数法 含量测定 |
| 文章编号： | 1001-0408(2003)03-0177-02 |
| 修稿时间： | 2002-04-04 |
Determination of the Contents of Three Ingredients in Compound Chloramphenicol Tincture by Multiwavelength Coefficient Spectrophotometry |
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| MIAO Chunhui,LENG Aiguo,TU Feilong. Determination of the Contents of Three Ingredients in Compound Chloramphenicol Tincture by Multiwavelength Coefficient Spectrophotometry[J]. China Pharmacy, 2003, 14(3): 177-178 |
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| Authors: | MIAO Chunhui LENG Aiguo TU Feilong |
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| Abstract: | OBJECTIVE:To establish a method for simultaneously determining chloramphenicol,salicylic acid and metroni_ dazole in compound chloramphenicol tincture with no need for separation.METHODS:The concentrations of three main inˉgredients were determined by multiwavelength coefficient spectrophotometry,the detecting wavelengths being277.5,297.0and317.0nm respectively.RESULTS:The average recoveries of chloramphenicol,salicylic acid and metronidazole were(100.22±0.74)%,(99.25±1.54)%and(99.79±1.92)%respectively.CONCLUSION:This method is simple,rapid and accurate.It is suitable for the determination of multicomonent preparation in hospital routine analysis. |
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| Keywords: | compound chloramphenicol tincture multiwavelength coefficient spectrophotometry content determination |
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