钙,硒对膳食低钙大鼠红细胞钠／钾ATP酶及钙／镁ATP酶活性的影响

实验通过向模拟克山病偏食饲料中补充一定量的钙和硒／维生素Ｅ（Ｓｅ／ＶＥ）来观察大鼠红细胞钠／钾ＡＴＰ酶及钙／镁ＡＴＰ酶（Ｎａ－Ｋ－ＡＴＰａｓｅ，Ｃａ－Ｍｇ－ＡＴＰａｓｅ）活性的变化。探讨钙和硒对大鼠ＲＢＣ膜的变化规律。结果表明，病区粮组血钙水平最低，仅及常规食（ｓｔｏｃｋ）组一半，血清硒（Ｓｅ），α－ＶＥ水平低于ｓｔｏｃｋ组，红细胞Ｎａ－Ｋ－ＡＴＰａｓｅ，Ｃａ－Ｍｇ－ＡＴＰａｓｅ，活性降低，血清过

INFLUENCE OF CALCIUM AND SELENIUM ON Na-K-ATPase AND Ca-Mg-ATPase ACTIVITIES IN RATS FED LOW CALCIUM DIET

In this experiment, the effects of mimic Keshan disease endemic monotonous diet (EM diet) and that supplemented with Ca, Se/VE on Na - K - ATPase and Ca - Mg - ATPase activities in rats were studied. Wistar rats were composed of 5 subgroup by weight and sex. Results showed that EM diet was composed of corn chiefly and Ca content was low prominently as well as Se. The serum Ca, Se, VE levels and Na - K - ATPase and Ca - Mg - ATPase activities, GSH - Px activity in rats of EM group were significantly lower than those of the stock group rats. That LPO level of serum was significantly higher in EM group rats thali that of stock group rats. When EM diet was supplemented Ca, Na - K - ATPase and Ca - Mg - ATPase activities were improved and Se, VE levels were no change. When EM diet was supplemented Se, VE, serum Se, VE, Na - K - ATPase and Ca - Mg - ATPase activities were markedly increased, LPO level decreased significantly in supplemented Ca, Se/VE groups. The study suggested that Ca, Se/VE affect Ca, Na - K - ATPase and Ca - Mg - ATPase activities of red cell markedly by systematic analysis.