高血压病人高尿酸血症与冠心病发生的关系

目的　探讨原发性高血压病人高尿酸血症与冠心病发生的关系。方法　经临床诊断的病人 6 8例 ,6 2例献血员及健康查体者设为对照。测定以上两组人员血中尿酸、肌酐、总胆固醇、低密度脂蛋白胆固醇。结果　冠心病组与高血压组比较血清尿酸、肌酐间有非常显著性差异 (P <0 0 1) ,低密度脂蛋白胆固醇亦有显著差异 (P <0 0 5 )。高血压患者血尿酸低密度脂蛋白胆固醇水平显著高于对照组 (P <0 0 5 )。结论　合并冠心病高血压患者血尿酸显著增高 ,高尿酸血症的高血压病人与冠心病的发生有很直接的关系 ,可能是致冠心病的危险因素之一。

Relationship of hyperuricemia with CAD in patients with hypertension

Objective To study the relationship of hyperuricemia with coronary artery disease(CAD) in patients with essential hypertension.Methods Serum levels of UA,CR,TC and LDL-C were measured in 68 patients with hypertension and 62 healthy controls.Results The results showed that the levels of serum UA,CR,TC and LDL-C were increased in hypertension patients with CAD than those in the patients with hypertension.The differences of serum UA,CR and LDL-C between the two groups were statistically significant(P<0 01,P<0 01,P<0 05,respectively).Conclusion The level of serum UA was increased in the hypertension patients with CAD,and CAD was significantly associated with serum level of UA in the patients with hypertension.