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Thrombospondins, tumor angiogenesis and breast cancer]
Authors:P Clézardin  G Bruno-Bossio  A Fontana  C M Serre  S Magnetto  L Frappart
Affiliation:INSERM Unité 403, Faculté de Médecine La?nnec, Lyon, France.
Abstract:Thrombospondin-1 and -2 are extracellular matrix proteins that are overexpressed in breast cancer tissue. Their role in breast cancer remains unknown. This article reviews the potential effects of thrombospondin-1 and -2 in breast cancer tumori genesis and metastatic dissemination.
Keywords:
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