Thrombospondins, tumor angiogenesis and breast cancer] |
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Authors: | P Clézardin G Bruno-Bossio A Fontana C M Serre S Magnetto L Frappart |
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Affiliation: | INSERM Unité 403, Faculté de Médecine La?nnec, Lyon, France. |
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Abstract: | Thrombospondin-1 and -2 are extracellular matrix proteins that are overexpressed in breast cancer tissue. Their role in breast cancer remains unknown. This article reviews the potential effects of thrombospondin-1 and -2 in breast cancer tumori genesis and metastatic dissemination. |
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