阳江天然放射性高本底辐射慢性照射与实体癌超额危险

放射治疗在食管癌的治疗中占有重要地位 ,然而常规放射治疗的疗效较差。随着放射生物学的发展 ,近年来发展起来的非常规分割放疗 ,取得了较好的疗效。本研究采用全程不均等加速超分割放射治疗的非常规方法进行了食管癌的临床Ⅰ Ⅱ期试验 ,结果报道如下。一、材料和方法1 一般临床资料 :1998年 5月～ 1998年 10月收治的食管癌患者 6 8例 ,男 42例 ,女 2 6例 ,年龄 34～ 76岁 ,卡氏评分(ＫＰＳ)≥ 70。能进流质饮食 ,病理证实为食管鳞癌患者 ,病灶长度 3～ 11ｃｍ ,≤ 5ｃｍ 2 8例 ,>5ｃｍ 40例。Ｂ超、胸部Ｘ射线片及体格检查均证实无远处转…

Excess relative risk for solid cancer mortality during prolonged exposure to high-background natural radiation in Yangjiang area of China

Objective To estimate the excess relative risk for solid cancer associated with chronically exposure to high-background natural radiation in Yangjiang area of China. Methods Based on hamlet-specific environmental doses and sex-and age-specific occupancy factors,we calculated cumulative doses for each cohort member.Assuming a linear dose response relationship and using cancer mortality data for the period 1979-1995 and Poisson model,we estimated the excess relative risk(EER)for solid cancer. Results The ERR per Sv of all solid cancer is estimated to be -0.11(95% CI,-0.67,0.69 to 95%).The corresponding figures for cancers of liver,nasopharynx,lungs and stomach are -0.99(-1.60,0.10),0.10(-1.21,3.28),-0.68(-1.58,1.66) and -0.27(-1.37,2.69)respectively. Conclusion The association between ERR of solid cancer and dose can not be found.