Comparative in vitro activities of five quinolone antibiotics, including gemifloxacin, against clinical isolates |
| |
| Authors: | N Gönüllü Z Akta&#; M &#;alciolu Ç Bal Ö An |
| |
| Institution: | Institute for Experimental Medical Research, University of Istanbul, Istanbul,;Department of Microbiology and Clinical Microbiology, Istanbul Faculty of Medicine, University of Istanbul, 4390 Çapa, Istanbul, Turkey and;Formerly at 2;Tel/Fax: +90 212635 11 86;E-mail: |
| |
| Abstract: | The in vitro activities of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin and gemifloxacin against 343 clinical isolates were compared. Gemifloxacin showed the greatest activity, with MIC90 values as low as 0.03–0.25 mg/L against Streptococcus pneumoniae , Haemophilus influenzae , Moraxella catarrhalis , methicillin-susceptible Staphylococcus aureus and Klebsiella pneumoniae , while methicillin-resistant Staphylococcus aureus , Enterococcus spp., Pseudomonas spp., Acinetobacter spp., Escherichia coli and Enterobacter spp. strains exhibited low rates of susceptibility to all five fluoroquinolones. |
| |
| Keywords: | Fluoroquinolones gemifloxacin MIC |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
