| 糖尿病肾病微量白蛋白尿期的治疗探索 |
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| 引用本文： | 于佩,张宏,于德民,董佳梅,赵伟,田原. 糖尿病肾病微量白蛋白尿期的治疗探索[J]. 天津医科大学学报, 2001, 7(2): 253-255 |
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| 作者姓名： | 于佩 张宏 于德民 董佳梅 赵伟 田原 |
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| 作者单位： | 天津医科大学代谢病医院, |
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| 摘 要： | 目的：探索糖尿病肾病的治疗方法。方法：将60例住院治疗的糖尿病微量白蛋白患者随机分成小剂量肝素治疗组和前列腺素E1治疗组，治疗15d后复查有关指标。结果：小剂量肝素与前列腺素E1皆可降低早期糖尿病肾病者尿微量白蛋白（均P＜0．05），治疗后两组间尿微量白蛋白无显著性差异（P＞0．05）；且肝素与前列腺素相比，有降低血压、改善血脂（降低TG、TC、LDL－C、VLDL及升高HDL－C）作用，两组间有显著性差异（P＜0．05）。结论 小剂量肝素治疗早期糖尿病肾病是一种安全、有效、经济的疗法。
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| 关 键 词： | 糖尿病 糖尿病肾病 肝素 治疗 |
| 文章编号： | 1006-8147(2001)02-0253-03 |
| 修稿时间： | 2001-01-09 |
To explore the treatment of early diabetic nephropathy |
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| YU Pei,ZHANG Hong,YU De-min,DONG Jia-mei,ZHAO Wei,TIAN Yuan. To explore the treatment of early diabetic nephropathy[J]. Journal of Tianjin Medical University, 2001, 7(2): 253-255 |
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| Authors: | YU Pei ZHANG Hong YU De-min DONG Jia-mei ZHAO Wei TIAN Yuan |
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| Abstract: | Objective: To explore the treatment of early diabetic nephropathy(DN). Methods: sixty early DN patients were randomly treated with either lower dosage heparin sodium or prostaglandin E1(PGE1).Then they were checked up on with related tests 15 days later. Results: Both groups showed that urine micro albumin decreased(P<0.05).There was no significant difference between the two groups (P>0.05).Otherwise, heparin can not only reduce blood pressure but improve hyperlipemia(decrease TG,TC,LDL-C,VLDL and increase HDL-C). There was a significant difference between the two groups (P<0.05). Conclusion: To treat with lower dosage heparin is a safe,effective and economical way to deal with early DN. |
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| Keywords: | Diabetic mellitus(DM) Early diabetic nephropathy Heparin |
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