腹部超声检查在诊断结节性硬化症中的应用价值

目的：探讨腹部超声在结节性硬化症诊断和随访中的价值。方法：分析112例结节性硬化症患者的腹部超声表现,对病变的特点进行总结。结果：112例结节性硬化症患者中B超发现65例（58.0%）有肾脏病变,累及双肾46例,累及单侧肾脏19例;肾脏错构瘤54例,多发47例,单发7例;肾囊肿20例,其中12例伴发肾脏错构瘤;肾脏多发钙化灶6例,其中3例和肾囊肿或肾脏错构瘤并发。15岁以上的年龄组肾脏病变的发生率（69.1%）高于15岁以下年龄组（47.4%）（P〈0.05）。肾脏错构瘤会随着年龄增长而增大。23例（20.5%）有肝脏病变,其中21例（91.4%）伴有肾脏病变,肝脏多发结节12例,单发结节11例。结论：腹部超声有助于结节性硬化症的诊断,是结节性硬化症肝肾病变的重要的影像学检查和随访方法。

Diagnostic Value of Abdominal Ultrasound Screening in Patients with Tuberous Sclerosis

Objective： To evaluate the value of abdominal ultrasound on diagnosis and prognosis of patients with tuberous sclerosis（TS）.Methods： Abdominal ultrasonographic findings were analyzed in 112 patients with TS from 1995 to 2009 in our hospital.Results： There were 65 patients（58.0%） with renal involvement,of which 46 were bilateral and 19 were unilateral.There were 54 patients with renal hamartomas,of which 47 were multiple and 7 were solitary.There were 20 patients with renal cysts,12 of them were accompanied by renal hamartomas.Six patients had multiple renal calcified foci,and 3 of them were associated with renal cysts or renal hamartomas.The incidence of renal involvement（69.1%） in patients over 15 years old was higher than that of patients under 15 years old（47.4%）,P0.05.Renal hamartomas increased in size with age.There were 23 patients（20.5%） with hepatic involvement and 21 of them（91.4%）were complicated with renal involvement,while 12 patients had multiple hepatic tubers and 11 patients had solitary hepatic tubers.Conclusions： Abdominal ultrasound is helpful to the diagnosis of TS,and it is an important imaging method to hepatorenal involvement and follow-up of TS.