| 珍稀中药资源金平人参的研究与利用2 |
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| 引用本文： | 李晓波,姜薇薇,张广辉,邓自有,王淞,田兴智,郭巧生,杨生超.珍稀中药资源金平人参的研究与利用2[J].中草药,2022,53(14):4568-4581. |
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| 作者姓名： | 李晓波 姜薇薇 张广辉 邓自有 王淞 田兴智 郭巧生 杨生超 |
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| 作者单位： | 云南农业大学 云南省药用植物生物学重点实验室/西南中药材种质创新与利用国家地方联合工程研究中心, 云南 昆明6502012. 云南农业大学农学与生物技术学院, 云南 昆明 6502013. 云南农业大学理学院, 云南 昆明 6502014. 金平苗族瑶族傣族自治县人民政府, 云南 红河 6615995. 金平大健康药材有限公司, 云南 红河 6615996. 南京农业大学中药材研究所, 江苏 南京 210095 |
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| 基金项目： | 国家重点研发计划(2017YFC1702500);云南省科技厅重大专项(2019ZF011-1);云南省科技厅重大专项(202102AA310048);云南省农业基础研究联合项目(2018FG001-037) |
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| 摘 要： | 金平人参Panax vietnamensis是一种珍贵的药用资源植物，分布于我国云南金平县一带以及越南的玉玲山和黄连山地区，野生资源稀缺，人工栽培初具规模。金平人参的化学成分主要为三萜皂苷类，目前已报道的皂苷类成分涉及奥克梯隆醇型、原人参二醇型、原人参三醇型、齐墩果酸型、C-17侧链变化型等共63个结构，其中奥克梯隆醇型皂苷珠子参苷R2含量最高，达5.3%。除此之外还有甾体皂苷、聚炔类、脂肪酸和氨基酸等成分。药理活性研究表明金平人参具有抗炎、抗肿瘤、抑制黑色素生成、肝肾保护、镇静安神等作用。对金平人参的资源现状、化学成分以及药理活性研究进行综述，以期为该植物的进一步开发利用提供依据。
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| 关 键 词： | 金平人参 资源 三萜皂苷 珠子参苷R2 抗炎 抗肿瘤 抑制黑色素生成 |
| 修稿时间： | 2021/11/4 0:00:00 |
Research and utilization of precious Chinese medicine resources of Panax vietnamensis |
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| LI Xiao-bo,JIANG Wei-wei,ZHANG Guang-hui,DENG Zi-you,WANG Song,TIAN Xing-zhi,GUO Qiao-sheng,YANG Sheng-chao.Research and utilization of precious Chinese medicine resources of Panax vietnamensis[J].Chinese Traditional and Herbal Drugs,2022,53(14):4568-4581. |
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| Authors: | LI Xiao-bo JIANG Wei-wei ZHANG Guang-hui DENG Zi-you WANG Song TIAN Xing-zhi GUO Qiao-sheng YANG Sheng-chao |
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| Institution: | The Key Laboratory of Medicinal Plant Biology of Yunnan Province, National and Local Joint Engineering Research Center on Germplasm Innovation and Utilization of Chinese Medicinal Materials in Southwest China, Yunnan Agricultural University, Kunming 650201, China 2. College of Agronomy and Biotechnology, Yunnan Agricultural University, Kunming 650201, China 3. College of Science, Yunnan Agricultural University, Kunming 650201, China 4. The People''s Government of Jinping Miao Yao Dai Autonomous County, Honghe 661599, China 5. Jinping Big Health Medicinal Materials Co., Ltd, Honghe 661599, China 6. Institute of Chinese Medicinal materials, Nanjing Agricultural University, Nanjing 210095, China |
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| Abstract: | Panax vietnamensis Ha et Grushv., is a precious medicinal plant, naturally distributed in the Jinping County in Yunnan, China, and Ngoc Linh and Hoang Lien Son mountain areas in Vietnam. Its wild resources are scarce, while artificial cultivation is beginning to take shape. The chemistry components isolated from P. vietnamensis were mainly triterpenoids, and the reported 63 saponin components related to ocotillol type, protopanaxadiol type, protopanaxatriol type, oleanolic acid type, and C-17 side-chain varied type, etc. Among them, the content of majonoside R2 was as high as 5.3%. In addition, it contents steroidal glycosides,polyacetylenes, fatty acids and amino acids, etc. Pharmacological studies showed that P. vietnamensis had the effects of anti-inflammatory, anti-tumor, melanin production inhibition, liver and kidney protection and sedation, etc. This article mainly summarized the current status on resources, chemical compositions, and pharmacological activities of P. vietnamensis in order to provide a reference for development and utilization of the plant. |
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| Keywords: | Panax vietnamensis Ha et Grushv |resources|triterpenoids|majonoside R2|anti-inflammatory|anti-tumor|inhibition of melanin production |
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