Functional analysis and treatment of problem behavior exhibited by children with fragile X syndrome |
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| Affiliation: | 1. Kennedy Krieger Institute, Baltimore, MD, United States;2. Johns Hopkins University School of Medicine, Baltimore, MD, United States;1. Faser Hall 236, Department of Pharmacy Administration, School of Pharmacy, The University of Mississippi, University, MS 38677, United States;2. Faser Hall 211, Department of Pharmacy Administration, School of Pharmacy, The University of Mississippi, University, MS 38677, United States;3. Faser Hall 223, PO Box 1848, Department of Pharmacy Administration, School of Pharmacy, The University of Mississippi, University, MS 38677, United States;1. Department of Community Psychology, Counseling, and Family Therapy, St. Cloud State University, United States;2. UK Young Autism Project, United Kingdom;3. Department of Behavioral Science, Oslo and Akershus University College, Norway;1. Institute for Community Inclusion (INICO). University of Salamanca, Spain;2. School of Social Work and Social Policy, Trinity College Dublin, Ireland;1. Kennedy Krieger Institute, USA;2. Johns Hopkins University School of Medicine, USA;3. Philadelphia College of Osteopathic Medicine, GA, USA |
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| Abstract: | The efficacy of function-based interventions for the treatment of severe problem behavior exhibited by individuals with intellectual and developmental disabilities (IDD) is well established. However, few studies have reported on behavioral interventions in fragile X syndrome (FXS) specifically. The present study is a consecutive case-series analysis that reports on functional analysis and treatment of problem behavior of nine children with FXS. Assessment findings were consistent with previous research indicating that among individuals with FXS, problem behavior is more commonly maintained by escape from demands and access to tangible items, relative to the broader population of individuals with IDD. Functional analysis-based behavioral interventions resulted in a mean reduction in problem behavior of 95.2% across the nine participants. Additionally, generalization of treatment effects from controlled clinical settings to home, school, and community was demonstrated. The current findings suggest that function-based behavioral interventions shown to be effective with the broader population of individuals with IDD are also effective for individuals with FXS. Our results in combination with those of previous studies describing functional analysis outcomes provide additional evidence for a unique functional behavioral phenotype for severe problem behavior in individuals with FXS. Implications of study findings for early intervention and prevention of problem behavior in children with FXS are discussed. |
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| Keywords: | Fragile X syndrome Problem behavior Self-injurious behavior Aggression Functional analysis Treatment Generalization |
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