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Postirradiation meningioma
Authors:Rinaldo Cantini  Marilena Burchianti  Maria Grazia Fabrini  Anna Maria Valleriani  Umberto Simi
Affiliation:(1) Institute of Neurosurgery, University of Pisa, S. Chiara General Hospital, Via Roma, I-56100 Pisa, Italy;(2) Institute of Radiology, University of Pisa, S. Chiara General Hospital, Via roma, I-56100 Pisa, Italy;(3) Department of Histology and Pathological Anatomy, University of Pisa, S. Chiara General Hospital, Via Roma, I-56100 Pisa, Italy
Abstract:A case of meningioma of the posterior cranial fossa is reported. The tumor developed 12 years after radiation treatment for a polar spongibolastoma of the cerebellum in an 8-year-old boy. The possible role of the radiation in the oncogenesis of the second tumor is discussed. In light of the information in the literature concerning the malignancy of such postirradiation tumors, the authors recommend careful evaluation for the real necessity of radiation therapy, particularly for children in whom the meninges may be hypersensitive to ionizing radiation.
Keywords:Brain tumor  Radiation-induced meningioma  Radiation therapy
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