| 实验性非胰岛素依赖性糖尿病模型探讨 |
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| 引用本文： | 刘欣秋,雷鸣. 实验性非胰岛素依赖性糖尿病模型探讨[J]. 黑龙江医药科学, 2001, 24(3): 18-18 |
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| 作者姓名： | 刘欣秋 雷鸣 |
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| 作者单位： | 1. 佳木斯大学基础医学院生理教研室
2. 佳木斯大学第二附属医院麻醉科 |
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| 摘 要： | 目的：复制非胰岛依赖型糖尿病（non insulin-dependent diabetes mellitus,NIDDM)模型，方法：给大鼠尾静脉注射小剂量链尿佐菌素，使大鼠糖耐量异常，然后加喂高热量食物，结果：8周后形成NIDDM模型。结论：胰岛素敏感指数可准确反应胰岛素受体数目的多少。
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| 关 键 词： | 胰岛素敏感指数 非胰岛素依赖性糖尿病 实验研究 |
| 修稿时间： | 2001-03-10 |
Model of rats with experimental non-insulin-dependent diabetes |
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| Liu Xinqiu,Lei Ming. Model of rats with experimental non-insulin-dependent diabetes[J]. Heilongjiang Medicine and Pharmacy, 2001, 24(3): 18-18 |
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| Authors: | Liu Xinqiu Lei Ming |
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| Affiliation: | Liu Xinqiu,Lei Ming1 |
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| Abstract: | Objective: To establish establishing a model of non-insulin dependent diabetes mellitus (NIDDM). Method: We injected rats with small dose streptozocoi (i.v.). Two weeks after the injection, the rats developed impaired glucose tolerance. Then, they were fed with high energy diet. Results: After eight weeks. NIDDM Model was formed. Insulin sensitive index was decreased compared with controls (P<0.01). Conclusion: Insulin sensitive index may show accurate the number of the insulin receptors. |
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| Keywords: | Non-insulin-dependent diabetes Insulin sensitive index |
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