Correlation of an exercise-induced increase in systemic circulation with neural retinal function in humans |
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Authors: | Hélène Kergoat Pierre Forcier |
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Institution: | (1) école d'Optométrie, Université de Montréal, Succursale Centre-ville, CP 6128, H3C 3J7 Montréal, Québec, Canada |
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Abstract: | Although the effects of physical exertion on intraocular pressure and systemic blood pressure are well established, the retinal
response to such physiologic stress has not been examined. We studied the effect of short-term intense exercise on the principal
waves in the scotopic and photopic flash electroretinograms, as well as the lower-amplitude oscillatory potentials. Sixteen
healthy volunteers between 20 and 30 years of age participated in this experiment. The electroretinograms and oscillatory
potentials were recorded with a Nicolet CA-1000 clinical averager, using DTL-type fiber electrodes. All retinal potentials
were taken immediately before and after a minimum 20-min period of stationary bicycling that increased the heart rate to about
140 beats per minute. The electroretinograms were recorded from eyes with dilated pupils, 10 min after white-light adaptation
of the right eye, and 30 min after dark adaptation of the left eye. Red flashes and dim white flashes were used to elicit
photopic and scotopic electroretinograms, respectively. While no changes were recorded for any of the electroretinogram components
recorded under photopic conditions, the amplitude of OP5 was decreased and the implicit time of OP4 was delayed after exercise
for scotopic conditions. We concluded that exercise caused component-specific changes in the scotopic oscillatory potentials.
Since it is well known that oscillatory potentials are vulnerable to ischemia, scotopic oscillatory potentials may be used
as simple noninvasive indices of the reactivity of the retinal vascular autoregulatory system during exercise. |
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Keywords: | Component-specific loss Electroretinogram Exercise Ocular perfusion pressure Oscillatory potentials |
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