Immunocytochemical detection of peptides in the guinea pig cochlea |
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| Authors: | R. Nowak A. Dorn H. -G. Bernstein A. Rinne H. J. Scholtz M. Ziegler |
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| Affiliation: | (1) Department of Oto-Rhino-Laryngology, Wilhelm-Pieck-University Rostock, DDR-2500 Rostock, German Democratic Republic;(2) Institute of Anatomy, Medical Academy Magdeburg, DDR-3090 Magdeburg, German Democratic Republic;(3) Institute of Pathology, University of Oulu, Finland;(4) Central Insitute of Diabetes, Karlsburg, German Democratic Republic |
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| Abstract: | Summary The cochleae of juvenile guinea pigs were investigated for the presence of several neuropeptides. Glucagon, insulin, CCK and  -endorphin immunoreactive neurons and nerve fibers as well as hair cells were demonstrated by the peroxidase antiperoxidase technique. Small amounts of substance P were also found in different sites in the inner ear. In contrast, prolactin-like material could not be found at all. These findings have significance with regard to the putative role of neuropeptides in neuromodulation. |
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| Keywords: | Cochlea Guinea pig Neuropeptides Immunolocalization |
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