检测胎儿型纤维连接蛋白用于诊断胎膜早破

应用ＡＢＣ抗体凝集素夹心斑点免疫法，对３０例正常妇女血浆、５０例正常孕妇宫颈分泌物和８０例胎膜早破孕妇宫颈分泌物，进行纤维连接蛋白（Ｆｎ）岩藻糖化异质体检测。结果：胎膜早破孕妇宫颈分泌物中Ｆｎ岩藻糖化异质体检出阳性纺为９５．０％，正常孕妇为６．０％。提示：胎儿型Ｆｎ对诊断胎膜早破有较高的敏感性。为胎膜早破的诊断提供了一个新方法。

Fetal Fibronectin Diagnosis of Premature Rupture of the Amniotic Membranes

bjective To determine whether fetal fibronectin is a sensitive test for the detection of premat-ure rupture of the amniotic membranes.Methods Fetal fibronectin by ABC immunoblotting methods were measured in samples of cervi-covaginal secretion from 80 cases with ruptured amniotic membranes (study group)and 50 cases of term pregnancy(control group A).Plasma fetal fibronectin were examined in 30 cases of normal pregnancy (control group B),Results The detection rate of fetal fibronectin in the women with ruptured membranes was 95.0%, While 6%in normal pregnancy. Conclusions Fetal fibronectin is a sensitive test for detection of present of amniotic fluid.It can be used for diagnosis of ruptured amniotic membranes.